New studies have found that in addition to the danger posed by the prematurity virus in the immediate term, it may cause complications in the lower respiratory tract throughout childhood.
Epidemiological data show a link between hospitalization at a young age as a result of RSV infection and chronic respiratory complications such as recurrent wheezing and asthma that may persist into adolescence.
In several large studies, it was found that the development of lower respiratory tract infections due to RSV infection in the first two years of life is a risk factor for the future development of wheezing and repeated wheezing up to the age of 11.
Summary of a study indicating a decrease of 50% in repeated wheezes among premature infants who received Singis compared to the control group:
The purpose of the study:
Children who experienced RSV infection in the lower respiratory tract at the beginning of their lives have an increased risk of repeated wheezing in the respiratory system. Palivizumab (monoclonal antibody) showed efficacy of 80% in preventing hospitalizations due to RSV among premature infants without chronic lung disease.
It is hypothesized that preventing RSV infection among premature infants may reduce recurrent wheezing among premature infants.
Methods:
191 premature infants who received prophylactic treatment against the RSV virus were compared to 230 premature infants who did not receive prophylactic treatment. A prospective follow-up was carried out for two years, when rates of repeated wheezes were checked, both by parental reports and by a doctor.
Results:
Among the premature infants who received the preventive treatment, a decrease of 50% was observed in rates of repeated wheezes, including repeated wheezes diagnosed by a doctor (26% vs. 16% and 13% vs. 8%).
conclusion:
The study indicates that preventing infection with the RSV virus in the lower respiratory tract by providing prophylactic treatment can reduce repeated wheezing among premature infants.
The Lehab Association - For Premature Infants in Israel (AR) is a nationwide association established by parents of premature infants and former premature infants for the purpose of promoting and improving the condition of premature infants in Israel, their families, and premature infants in Israel and to reduce the number of premature infants born each year and increase awareness of the dangers of miscarriages.
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